• Users Online: 147
  • Print this page
  • Email this page
CASE REPORT
Year : 2019  |  Volume : 6  |  Issue : 4  |  Page : 203-207

A 54-year-old man with primary mediastinum choriocarcinoma


Division of Hematology/Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Keelung and Chang Gung University, College of Medicine, Taiwan

Correspondence Address:
Dr. Cheng-Hsu Wang
Division of Hematology/Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Keelung and Chang Gung University, College of Medicine, 200, Lane 208, Jijin 1st Road, Keelung 20445
Taiwan
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/JCRP.JCRP_22_19

Rights and Permissions

Primary mediastinum choriocarcinoma, an extragonadal germ cell tumor, is a rare malignant tumor that is more common in men. We present a case of primary mediastinum choriocarcinoma in a male patient who initially presented with gynecomastia and progressed to superior vena cava syndrome. Both surgical biopsy and pathologic diagnosis were challenging. After standard induction chemotherapy, the resected tumor underwent squamous cell transformation, which has rarely been reported in cases of choriocarcinoma. His critical condition was resolved using induction chemotherapy with a combination of bleomycin, etoposide, and cisplatin, followed by resection of the residual tumor. However, tumor recurrence occurred 9 months later, and he was treated with salvage radiotherapy and chemotherapy. This was a rare and challenging case from the aspects of initial approaches, pathologic differential diagnosis, and different treatment modalities.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed48    
    Printed0    
    Emailed0    
    PDF Downloaded17    
    Comments [Add]    

Recommend this journal