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CASE REPORT
Year : 2020  |  Volume : 7  |  Issue : 1  |  Page : 38-40

Very late relapse of plasma cell myeloma after allogeneic hematopoietic stem cell transplantation


1 Department of Internal Medicine, E-Da Hospital, Kaohsiung, Taiwan
2 Division of Hematology-Oncology, Department of Internal Medicine, E-Da Hospital; School of Medicine, I-Shou University, Kaohsiung, Taiwan
3 Division of Hematology-Oncology, Department of Internal Medicine, E-Da Hospital, Kaohsiung, Taiwan

Correspondence Address:
Dr. Yu-Chieh Su
Division of Hematology-Oncology, Department of Internal Medicine, E--Da Hospital, No.1, Yida Rd., Yanchao Dist., Kaohsiung 82445
Taiwan
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/JCRP.JCRP_23_19

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Very late (more than 10 years) relapse of plasma cell myeloma after allogeneic hematopoietic stem cell transplantation (allo-HSCT) is rare. The most common relapse pattern in such cases involves the bone marrow. Here, we report the case of a 51-year-old woman whose myeloma relapsed 15 years after allo-HSCT. She retained full donor chimerism, and the myeloma presented as soft tissue in the colonic wall. According to our review of the literature, this case presents the longest time to relapse after allo-HSCT. Patients with myeloma who undergo allo-HSCT should continue to receive regular follow-up even after 15 years.


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