Journal of Cancer Research and Practice

: 2020  |  Volume : 7  |  Issue : 2  |  Page : 85--89

Angiosarcoma of the scalp: What is the optimum management?

Kaalindi Singh, Thomas Samuel Ram, Jebakarunya Rami Reddy, Arvind Murthy 
 Department of Radiation Oncology, CMC Hospital, Vellore, Tamil Nadu, India

Correspondence Address:
Dr. Kaalindi Singh
Department of Radiotherapy, CMC Hospital, Vellore - 632 004, Tamil Nadu

Scalp angiosarcoma is a rare malignancy with a poor outcome. In the absence of randomized trials, the approach to management depends on retrospective series and case reports. Here, we report a 56-year-old male diagnosed initially with squamous cell carcinoma of the scalp at an outside center. When he underwent re-excision for recurrence in our center, histopathology showed a high-grade angiosarcoma. He was offered postoperative radiotherapy for the primary site. During the treatment, he developed preauricular nodal recurrence, which was also treated with radiotherapy. After radiotherapy, he had persistent preauricular nodes, for which single-agent chemotherapy was given, and the nodes were regressed. However, the recurrence of preauricular nodes was noted at the next follow-up visit, and he was re-evaluated with a positron emission tomography-computed tomography scan, which showed an extensive lung and nodal metastases. He was started on metronomic chemotherapy and his disease was stable at the time of the last follow-up. This case raises several questions, including whether electively addressing the regional nodes in the scalp angiosarcoma could improve the outcomes, whether higher doses of radiotherapy are beneficial or only add to the toxicity of treatment, the role that chemotherapy plays and the most appropriate regimen. Although some relevant studies have been discussed in brief, more evidence is needed to answer these questions.

How to cite this article:
Singh K, Ram TS, Reddy JR, Murthy A. Angiosarcoma of the scalp: What is the optimum management?.J Cancer Res Pract 2020;7:85-89

How to cite this URL:
Singh K, Ram TS, Reddy JR, Murthy A. Angiosarcoma of the scalp: What is the optimum management?. J Cancer Res Pract [serial online] 2020 [cited 2021 Oct 24 ];7:85-89
Available from:;year=2020;volume=7;issue=2;spage=85;epage=89;aulast=Singh;type=0